Thermo Fisher Scientific MCAK Polyclonal Antibody
Rabbit polyclonal antibody targeting mouse MCAK protein. Validated for WB, IHC, IHC-P, and IP applications. Supplied as unconjugated liquid at 1 mg/mL concentration. Recommended storage at 4°C and shelf life of 1 year. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 50 and 100 of mouse Mitotic Centromere-Associated Kinesin (MCAK, UniProt ID: Q922S8-1, NCBI Node ID: 10090, antigen length: 721) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Rat
Target Information
The transport of molecules between the nucleus and cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60–100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion, while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family and is involved in nuclear protein import.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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