Thermo Fisher Scientific CCNDBP1 Polyclonal Antibody
Human CCNDBP1 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot과 IHC(Paraffin)에서 검증됨. 항원 친화 크로마토그래피로 정제된 액상 형태. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 298–360 of Human CCNDBP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545932 |
Product Specific Information
- Recommended positive control: Cyclin-D1-binding protein 1 transfected 293T cell
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
The CCNDBP1 gene was identified by its interaction with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The encoded protein interacts with cyclin D, reduces phosphorylation of the Rb gene product by cyclin D-dependent kinase, and inhibits E2F1-mediated transcription activity. It also interacts with helix-loop-helix protein E12 and may act as a negative regulator of liver-specific gene expression. Two alternatively spliced variants encoding distinct isoforms have been reported.
주의사항
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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