Thermo Fisher Scientific CD274 Polyclonal Antibody, FITC
FITC 형광 표지된 CD274(PD-L1) 폴리클로널 항체로 인간, 마우스, 랫트 시료에 반응. Western blot과 유세포 분석에 적합. 고순도 Protein A 정제, 높은 감도와 재현성 제공. 암 면역 회피 연구용으로 최적화.
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–5,000
Flow Cytometry (Flow)
- Tested Dilution: 1:20–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human CD274 (amino acids 61–160) |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. PD-L1 binds to its receptor PD-1, which negatively regulates T-cell receptor (TCR) signaling. Upon ligation, PD-L1 decreases TCR-mediated proliferation and cytokine production. PD-L1 is abundantly expressed on many murine and human cancers and can be up-regulated by IFN-gamma stimulation, suggesting an important role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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