Thermo Fisher Scientific EVER2 Polyclonal Antibody
EVER2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western Blot, IHC, ICC/IF에 적합하며 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체로 연구용에 최적화.
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Thermo Fisher Scientific EVER2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
| Immunocytochemistry (ICC/IF) | 20 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 14 amino acid peptide from near the center of human EVER2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153881 |
Product Specific Information
- Suggested positive control: Jurkat cell lysate
- PA5-20526 can be used with blocking peptide PEP-0646
Target Information
Epidermodysplasia verruciformis (EV) is an autosomal recessive genodermatosis associated with a high risk of skin cancers resulting from a high susceptibility to infection by specific human papillomaviruses.
Mutations in two homologous genes, EVER1 and EVER2, cause the majority of EV cases. These proteins form a complex and interact with the zinc transporter ZnT-1 in the endoplasmic reticulum.
Cells lacking EVER2 accumulate higher levels of zinc in the nucleolus and nucleus compared to those with an intact EVER2 gene, indicating that one role of EVER2 is to regulate intracellular zinc distribution.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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