Thermo Fisher Scientific CD68 Recombinant Rabbit Monoclonal Antibody (SN07-27)
Human CD68 단백질을 인식하는 재조합 토끼 단일클론 항체로, Western blot에 최적화되어 있습니다. HEK293 세포에서 발현되며 높은 특이성과 재현성을 제공합니다. Protein A로 정제된 액상 형태이며, TBS buffer(40% glycerol, 0.05% BSA)로 안정화되어 있습니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SN07-27 |
| Immunogen | Synthetic peptide within Human CD68 (aa 21–70) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809585 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to larger rabbit immune repertoire
Target Information
CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on intracellular lysosomes of monocytes and macrophages, and to a lesser extent by dendritic cells and granulocytes. It plays a role in phagocytic activities of tissue macrophages, including intracellular lysosomal metabolism and extracellular interactions.
CD68 is expressed by interdigitating reticulum cells in tonsil and certain histiocytic lymphomas, histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been observed on CD34+ cells in various human malignancies, including several AML studies.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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