
Thermo Fisher Scientific FGFR2 Monoclonal Antibody (OTI3F8), TrueMAB
FGFR2 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, Western blot, IHC, ICC/IF 등에 사용 가능. Human 시료 반응성, Lyophilized 형태로 제공되며 고순도 친화 크로마토그래피 정제. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3F8 |
| Immunogen | Full length human recombinant FGFR2 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
FGFR2 (Fibroblast Growth Factor Receptor 2) belongs to the FGFR family of receptor tyrosine kinases that regulate cellular processes such as angiogenesis, mitogenesis, osteogenesis, myogenesis, and tissue repair.
Mutations in FGFR2 are associated with multiple syndromes including Crouzon, Pfeiffer, Apert, Jackson-Weiss, Beare-Stevenson, Saethre-Chotzen, and syndromic craniosynostosis.
Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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