Thermo Fisher Scientific TSC22D4 Polyclonal Antibody
Rabbit polyclonal antibody targeting human TSC22D4 (residues 345–395). Validated for Western blot and immunoprecipitation. Supplied as 1 mg/mL liquid, unconjugated. Ideal for transcriptional regulation and metabolic research applications.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 345 and 395 of Human TSC22 Domain Family, Member 4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
Target Information
TSC22D4 is a member of the TSC22 domain family of leucine zipper transcriptional regulators.
Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity.
An important paralog of this gene is TSC22D1.
TSC22D4 binds DNA and acts as a transcriptional repressor (PubMed:10488076).
It regulates glucose homeostasis and insulin sensitivity via repression of downstream insulin signaling targets such as OBP2A/LCN13 (By similarity).
Acts as a negative regulator of lipogenic gene expression in hepatocytes, controlling very low-density lipoprotein release (PubMed:23307490).
May also play a role in neurite elongation and survival (By similarity).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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