Thermo Fisher Scientific RelB Polyclonal Antibody
RelB 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot, IHC, IP, ChIP 등에 사용 가능. 인간 및 생쥐 반응성, 항원 친화 크로마토그래피로 정제됨. 고농도 액상 형태로 장기 보관 시 -20°C 권장.
- 카탈로그번호
- PA527679
- 판매단위
- pk
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Thermo Fisher Scientific RelB Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunoprecipitation (IP) | 1:100–1:500 | - |
| ChIP assay (ChIP) | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 354–528 of Human RelB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.42 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545155 |
Product Specific Information
- Recommended positive controls: Raji, NCI-H929, NIH-3T3, RelB-transfected 293T
- Predicted reactivity: Mouse (83%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The NFkB transcription factor was originally identified as a protein complex consisting of a DNA-binding subunit and an associated protein.
The DNA-binding subunit is functionally related to c-Rel p75 and Rel B p68.
The p50 subunit was initially believed to be a unique protein derived from the amino-terminus of a precursor designated p105.
A second protein, p52 (previously p49), has been identified that can act as an alternative NFkB subunit.
Rel B does not bind with high affinity to NFkB sites, but heterodimers between Rel B and p50 bind with comparable affinity to p50 NFkB homodimers.
Rel B/p50 heterodimers, unlike NFkB heterodimers, transactivate transcription of promoters containing kB binding sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(해당 이미지: PA5-27679_RelB_Q01201-1_Rabbit.svg, PA5-27679_RelB_Q01201-1_Rabbit_PDP.jpeg)
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