Thermo Fisher Scientific TRAF2 Polyclonal Antibody
TRAF2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 인간, 생쥐, 랫트 반응성. 항원 친화 크로마토그래피로 정제되어 고순도(>95%) 확보. 연구용으로만 사용 가능.
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Thermo Fisher Scientific TRAF2 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the N-terminus of Human TRAF2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2802887 |
Product Specific Information
- Purity is >95% by SDS-PAGE.
Target Information
Tumor necrosis factor (TNF) receptor-associated factors (TRAFs) act as adaptor proteins linking the TNF receptor superfamily to signaling pathways, regulating cell death and stress responses. TRAF proteins share a conserved region enabling interactions with cell receptors and other TRAFs, activating distinct signal cascades. TRAF2 and TRAF3 bind directly to CD40, a receptor involved in B cell immunity, and are essential for NF-kappa-B activation in mouse B lymphocytes. TRAF2, together with TRAF6, is required for CD40 signaling in nonhematopoietic cells. Additionally, TRAF2 interacts with lymphotoxin-beta receptor (LTbetaR) alongside TRAF3 and apoptosis inhibitors cIAP1 and Smac.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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