Thermo Fisher Scientific Phospho-MEK1/MEK2 (Ser222) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

View 2 publications 2 publications

Immunocytochemistry (ICC/IF)

Assay-dependent

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Immunogen is a sequence surrounding the phosphorylated Ser222 of MEK1/2. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MEK1/2,uniProtId:Q02750-1,ncbiNodeId:9606,antigenRange:222,antigenLength:393,antigenImageFileName:44-452_MEK12_Q02750-1_Rabbit.svg,antigenImageFileNamePDP:44-452_MEK12_Q02750-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:MEK1/2,uniProtId:P36507-1,ncbiNodeId:9606,antigenRange:222,antigenLength:400,antigenImageFileName:44-452_MEK12_P36507-1_Rabbit.svg,antigenImageFileNamePDP:44-452_MEK12_P36507-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography

Storage buffer

Dulbecco`s PBS, pH 7.3, with 1mg/mL BSA

Contains

0.05% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2533654

Target Information

MEK 1 (MAP Kinase Kinase, also known as MKK) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation (Ahn, 1993; Chong et al., 2003). In brain, this pathway also plays a key role in synaptic (Adams and Sweatt, 2002). Activated MEK 1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase (Kyriakis et al., 1991; Seger et al., 1991; Crews et al., 1992).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.