Thermo Fisher Scientific ZNF268 Polyclonal Antibody
ZNF268 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 및 생쥐 시료에 반응하며 IHC, ICC/IF 등 다양한 응용에 적합. 고순도 Protein A 정제 및 안정적인 액상 형태로 제공.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200
Immunohistochemistry (Frozen) (IHC (F))
- Tested Dilution: 1:100–1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human ZNF268 (amino acids 286–358) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS (pH 7.4), with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Zinc-finger proteins contain DNA-binding domains and have diverse functions, primarily involving transcriptional activation or repression. Most zinc-finger proteins possess a Krueppel-type DNA binding domain and a KRAB domain, which interacts with KAP1 to recruit histone-modifying proteins.
Zinc finger protein 268 (ZNF268), also known as zinc finger protein 3 or HZF3, is a 947 amino acid protein belonging to the Krueppel C2H2-type zinc-finger family. It contains 24 C2H2-type zinc fingers and one KRAB domain. Localized in the nucleus, ZNF268 is involved in transcriptional regulation and is highly expressed in 3–5 week-old embryos.
ZNF268 has been implicated in human leukemia, with alternatively spliced forms identified in leukemia patients. Two named isoforms exist due to alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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