Thermo Fisher Scientific Laminin alpha-5 Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:2,000 dilution

Product Specifications

Product Specific Information

Antibody detects endogenous levels of total LAMA5.

Target Information

Components of the extracellular matrix exert myriad effects on tissues throughout the body. Laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in organs such as the kidney, lung, skin, and nervous system. Laminins mediate cell attachment, migration, and organization into tissues during embryonic development by interacting with other extracellular matrix components. They function as heterotrimeric complexes of alpha, beta, and gamma chains. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, though the full-length nature of one remains undetermined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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