Thermo Fisher Scientific ADAMTS1 Monoclonal Antibody (OTI1B4), TrueMAB
ADAMTS1 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western Blot에 최적화되었습니다. 인간 유래 항원(aa 412-644)으로 제작되었으며, 동결건조 형태로 제공됩니다. 재구성 시 1 mg/mL 농도로 사용 가능하며, 연구용으로 적합합니다.
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Applications
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 412–644 of human ADAMTS1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
ADAMTS-1 belongs to the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family.
These proteins share modules such as a propeptide region, metalloproteinase domain, disintegrin-like domain, and thrombospondin type 1 (TS) motif.
ADAMTS-1 contains two disintegrin loops and three C-terminal TS motifs, exhibiting anti-angiogenic activity. Its expression is associated with inflammatory processes and cancer cachexia, and is essential for normal growth, fertility, and organ morphology and function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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