
Thermo Fisher Scientific PRKG2 Monoclonal Antibody (OTI15E6), TrueMAB
Human PRKG2 단백질을 표적으로 하는 Mouse IgG1 모노클로날 항체로, Western blot에 적합. Lyophilized 형태로 제공되며, 재구성 후 1 mg/mL 농도. PBS buffer와 trehalose 포함, 보존제 없음. 연구용으로 사용.
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Applications
Tested Dilution
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI15E6 |
| Immunogen | Human recombinant protein fragment (aa 40–320 of human PRKG2) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
PRKG2 (PKG2, cGKII) is a cAMP- and cGMP-dependent protein kinase involved in diverse cellular functions. It may mediate intestinal water and electrolyte secretion induced by E. coli toxin STa and guanylin.
cGKII is proposed to act as a molecular switch linking cessation of proliferation to hypertrophic chondrocyte differentiation by attenuating SOX9 function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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