
Thermo Fisher Scientific Human Plateable Hepatocytes, Uptake Qualified
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Gibco™
Human Plateable Hepatocytes, Uptake Qualified
Cryopreserved human hepatocytes for use in transporter-mediated uptake applications.Cells per vial: 4-8 million Prototypical hepatic uptake transporter substrates taurocholate and자세히 알아보기
Cryopreserved human hepatocytes for use in transporter-mediated uptake applications.
Cells per vial: 4-8 million
Prototypical hepatic uptake transporter substrates taurocholate and estradiol-17β-glucuronide have been assessed to qualify the transport function of hepatic NTCP (SLC10A1) and OATP1B14/3 (SLCO1B1/3), respectively. The transport of each substrate (radiolabeled) was monitored by scintillation analysis and active transport values (37°C - 4°C) determined by linear regression.
Get the Results You Need with GIBCO™ Hepatocytes
High quality hepatocytes, with high viabilities, in vivo_-like enzyme expression levels, and proper cell morphology increase the ability to draw _in vitro/in vivo correlations and make sound decisions regarding a compound`s fate. Experienced technicians and proprietary isolation techniques combined with stringent release specifications ensure you receive the highest quality cryopreserved hepatocytes.
Each lot is tested for:
• Phase I and II enzyme activities
• Proper morphology
• Viabilities generally >75%
• Attachment efficiency
• Monolayer formation and integrity
For research use only. Not intended for human or animal therapeutic or diagnostic use.
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사양
셀 패시지 수Passage 0
셀 유형Hepatocytes
Culture TypeAdherent Cell Culture
형태Cryopreserved
종Human
공여자 소스Single Donor
형식Tube
셀 수4-8 x 106
제품라인Gibco™
제품 유형Hepatocytes
수량1.5 mL
Unit SizeEach
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