Thermo Fisher Scientific ERK1/ERK2 Polyclonal Antibody
ERK1/ERK2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등 다양한 응용에 사용 가능. Human, Mouse, Rat 등 다양한 종에 반응하며, 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용.
- 카탈로그번호
- 617400
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- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 24 publications |
| Immunohistochemistry (IHC) | Assay-dependent | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | View 1 publication |
| ELISA | Assay-dependent | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rabbit, Rat |
| Published Species | Human, Mouse, Non-human primate, Rat, Xenopus |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (a.a. 339–353) corresponding to a C-terminal segment of rat ERK1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533939 |
Target Information
ERK1 and ERK2 are widely expressed and are involved in the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells.
Many different stimuli, including growth factors, cytokines, virus infection, ligands for heterotrimeric G protein-coupled receptors, and transforming agents, activate the ERK1 and ERK2 pathways.
Upon activation, the ERKs phosphorylate cytoplasmic targets or migrate to the nucleus, where they activate transcription factors such as c-Fos and Elk-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: 61-7400_ERK12_P63086-1_Rabbit.svg, 61-7400_ERK12_P63086-1_Rabbit_PDP.jpeg)
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