Thermo Fisher Scientific MOT8/SLC16A2 Polyclonal Antibody
MOT8/SLC16A2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, ICC/IF, Flow, ELISA 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. 고순도 Protein A 정제 및 안정적 액상 형태로 연구용에 최적화.
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Thermo Fisher Scientific MOT8/SLC16A2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 3 µg |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human MOT8/SLC16A2 (amino acids 101–200) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Monocarboxylates such as lactate and pyruvate play a key role in cellular metabolism. Lactic acid, produced during glycolysis, must be transported out of the cell to maintain pH and metabolic activity. This transport is mediated by monocarboxylate transporters (MCTs), which function as proton symports selective for L-lactate. The MCT family includes at least eight members (MCT1–8), each with 10–12 transmembrane domains. Mutations in the MCT8 gene (SLC16A2) can lead to monocarboxylate transporter 8 deficiency, an X-linked disorder affecting hormone transport and causing severe psychomotor retardation and abnormal thyroid levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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