Thermo Fisher Scientific ZBED1 Monoclonal Antibody (OTI1D5), TrueMAB
ZBED1 단백질을 인식하는 마우스 단클론 항체로, Western blot에 최적화되어 있습니다. 인간 유래 단백질을 면역원으로 제작되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 세포 증식 관련 연구용에 적합하며, -20°C에서 보관합니다.
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Applications
- Western Blot (WB): 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D5 |
| Immunogen | Full-length human recombinant protein of human ZBED1 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ZBED1 (also known as DREF) is the human homolog of the Drosophila DREF protein, a transcriptional regulatory factor required for expression of genes involved in DNA replication and cell proliferation.
RNA interference (RNAi) experiments targeting ZBED1 RNA resulted in inhibition of S phase entry and reduction of histone H1 mRNA in HeLa cells, suggesting a role in cell proliferation in human cells.
At least 22 ribosomal proteins (RPs) possess ZBED1 binding sites in their promoters; anti-ZBED1 RNAi also resulted in decreased RP gene expression.
Immunoprecipitation analyses have shown that ZBED1 self-associates in vivo via a carboxyl-terminal hATC domain, which is required for nuclear localization and DNA binding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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