Thermo Fisher Scientific FOXJ1 Polyclonal Antibody
Human FOXJ1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot에 적합합니다. 보존제가 없는 액상 형태이며, Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용되며, 장기 보관 시 -20°C에서 냉동 보관을 권장합니다.
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Thermo Fisher Scientific FOXJ1 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the center region of the Human FOXJ1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787935 |
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human FOXJ1.
Target Information
Forkhead-box J1 (FOXJ1) is a 421-amino acid transcription factor that suppresses T cell activity and spontaneous autoimmunity through repression of NF-κB activity. It also inhibits the humoral immune response in B cells.
FOXJ1 deficiency in B cells results in spontaneous and accentuated germinal center formation and is implicated in the development of pathogenic autoantibodies and accentuated responses to immunizations.
Abnormal expression of FOXJ1 may be associated with autoimmune and other inflammatory diseases. FOXJ1 is also required for cilia formation and left-right axis determination because it increases calpastatin expression, which is necessary for basal bodies to anchor to the apical cytoskeleton.
FOXJ1 expression may serve as an early marker of epithelial cell differentiation, recovery, and function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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