Thermo Fisher Scientific STC1 Polyclonal Antibody
STC1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 Immunocytochemistry에 적합합니다. 인간 시료에 반응하며, 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되었으며, -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human STC1 (Accession P52823), corresponding to amino acid residues K185–S235. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852455 |
Product Specific Information
Antibody detects endogenous levels of total Stanniocalcin 1.
Target Information
This gene encodes a secreted, homodimeric glycoprotein expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5′ UTR rich in CAG trinucleotide repeats. The encoded protein has 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. It may regulate renal and intestinal calcium and phosphate transport, cell metabolism, or calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. Altered expression has been observed in hepatocellular, ovarian, and breast cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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