Thermo Fisher Scientific TK1 Polyclonal Antibody
Human TK1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 ICC/IF에서 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS와 50% 글리세롤에 보관. 세포 분열 관련 연구 및 TK1 단백질 검출에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Thymidine Kinase 1 (soluble), corresponding to amino acid range 2–234 of the target protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903958 |
Target Information
Thymidine Kinase (TK1) is a highly conserved phosphotransferase present in most living cells. It catalyzes the phosphorylation reaction:
deoxythymidine + ATP → deoxythymidine 5'-phosphate + ADP.
This enzyme is involved in DNA synthesis and is essential for the incorporation of deoxythymidine into DNA. TK1 is required for the action of many antiviral drugs (e.g., azidothymidine, AZT) and is used in hybridoma selection for monoclonal antibody production. It has clinical relevance as it is expressed primarily during cell division.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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