Thermo Fisher Scientific ATP1A1 Recombinant Rabbit Monoclonal Antibody (4C3)

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:50–1:200

ELISA

• Tested Dilution: Assay-dependent

Product Specifications

Target Information

The protein encoded by this gene belongs to the family of P-type cation transport ATPases and to the subfamily of Na⁺/K⁺-ATPases. Na⁺/K⁺-ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, sodium-coupled transport of various organic and inorganic molecules, and electrical excitability of nerve and muscle.
This enzyme is composed of two subunits: a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na⁺/K⁺-ATPase is encoded by multiple genes, and this gene encodes the alpha 1 subunit. Multiple transcript variants encoding different isoforms have been identified.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.