Thermo Fisher Scientific AKT1 Monoclonal Antibody (3A3)
AKT1 단백질 검출용 Thermo Fisher Scientific 단클론 항체. Western blot과 ELISA에 적합하며 인간, 생쥐, 비인간 영장류 시료에 반응. 비결합형 액상 형태로 제공되며 4°C 단기, -20°C 장기 보관 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3A3 |
| Immunogen | Purified recombinant fragment of human AKT1 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10986567 |
Product Specific Information
MA5-15591 targets AKT1 in indirect ELISA and WB applications, showing reactivity with human, mouse, and non-human primate samples.
The immunogen is a purified recombinant fragment of human AKT1 expressed in E. coli.
MA5-15591 detects AKT1, which has a predicted molecular weight of approximately 56 kDa.
Target Information
AKT1 (PKB alpha) is a serine/threonine kinase that regulates cell survival. The activated enzyme inhibits apoptosis and stimulates cell cycle progression by phosphorylating numerous targets in various cell types, including cancer cells.
This protein kinase is activated by insulin, PI3K, IGF1, and various other growth and survival factors. Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of several targets, including forkhead transcription factors and caspase-9.
The AKT pathway is a major target for cancer drug discovery.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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