Thermo Fisher Scientific SDHB Monoclonal Antibody (OTI1H6), TrueMAB
SDHB 단백질을 인식하는 마우스 모노클로날 항체로, Western blot 및 IHC(P) 분석에 사용 가능. 인간, 마우스, 랫트 반응성. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도. 미토콘드리아 복합체 II 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H6 |
| Immunogen | Full length human recombinant protein of human SDHB produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Complex II of the mitochondrial respiratory chain participates in succinate oxidation, transferring electrons from FADH to CoQ.
It comprises four nuclear-encoded subunits localized in the mitochondrial inner membrane.
The iron-sulfur subunit is conserved and contains three cysteine-rich clusters forming the enzyme's iron-sulfur centers.
Mutations in this gene are associated with paragangliomas and pheochromocytomas, linking mitochondrial dysfunction to tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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