Thermo Fisher Scientific CD44v6 Monoclonal Antibody (MA54)
CD44v6 단백질을 인식하는 MA54 클론 단일클론 항체로, 인간 시료에 반응합니다. Western blot, IHC, ICC 등 다양한 응용에 적합합니다. 액상 형태로 제공되며, 고순도 친화 크로마토그래피로 정제되어 안정적입니다.
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Thermo Fisher Scientific CD44v6 Monoclonal Antibody (MA54)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | View 3 publications |
| Immunohistochemistry (IHC) | Assay-dependent | View 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | - | View 2 publications |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | View 1 publication |
| in situ PLA (PLA) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MA54 |
| Immunogen | Epitope encoded by exon v6 on the variant portion of human CD44 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533134 |
Target Information
CD44 cell surface antigen is a 100 kDa glycoprotein widely expressed on human leukocytes, white matter of the brain, and by some epithelial cells of the intestine and breast. Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues.
CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, adhesion, and migration. It participates in various cellular functions including lymphocyte activation, recirculation, and homing.
CD44 expression may be up-regulated in some carcinomas, potentially related to metastatic potential.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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