Thermo Fisher Scientific NIPA Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human NIPA. Recombinant protein control fragment (Product #RP-92633). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NIPA,uniProtId:Q86WB0-1,ncbiNodeId:9606,antigenRange:242-331,antigenLength:502,antigenImageFileName:PA5-54954_NIPA_Q86WB0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54954_NIPA_Q86WB0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644684

Product Specific Information

Immunogen sequence: IQVHVTACIL SVCGWACSSS LESMQLSLIT CSQCMRKVGL WGFQQIESSM TDLDASFGLT SSPIPGLEGR PERLPLVPES PRRMMTRSQD

Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%.

Target Information

This gene encodes an F-box-containing protein that is a component of an SCF-type E3 ubiquitin ligase complex that regulates the onset of cell division. The G2/M transition in the cell cycle requires the interaction of the proteins cyclin B1 and cyclin-dependent kinase 1. The activated ubiquitin ligase complex targets the protein cyclin B1 for degradation, preventing this transition to mitosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.