Thermo Fisher Scientific NIPA Polyclonal Antibody
Thermo Fisher Scientific의 NIPA Polyclonal Antibody는 Human, Mouse, Rat에서 반응하며 Western blot, IHC, ICC/IF에 적합합니다. Rabbit IgG 기반의 비결합 항체로, 고순도 항원 친화 크로마토그래피로 정제되었습니다. 세포주기 조절 연구에 활용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NIPA. Recombinant protein control fragment (Product #RP-92633). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644684 |
Product Specific Information
Immunogen sequence:
IQVHVTACIL SVCGWACSSS LESMQLSLIT CSQCMRKVGL WGFQQIESSM TDLDASFGLT SSPIPGLEGR PERLPLVPES PRRMMTRSQD
Ortholog identity:
Mouse – 86%, Rat – 86%
Target Information
This gene encodes an F-box-containing protein that is a component of an SCF-type E3 ubiquitin ligase complex that regulates the onset of cell division.
The G2/M transition in the cell cycle requires the interaction of the proteins cyclin B1 and cyclin-dependent kinase 1.
The activated ubiquitin ligase complex targets cyclin B1 for degradation, preventing transition to mitosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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