Thermo Fisher Scientific NeuroD1 Polyclonal Antibody
NeuroD1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 ICC/IF에 사용 가능. 인간 시료에 반응하며 항원 친화 크로마토그래피로 정제됨. 장기 보관 시 -20°C에서 보관 권장.
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Thermo Fisher Scientific NeuroD1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NEUROD1 (Product #RP-100735) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789236 |
Product Specific Information
Immunogen sequence:
ASFPVHPYSY QSPGLPSPPY GTMDSSHVFH VKPPPHAYSA ALEPFFESPL TDCTSPSFDG PLSPPLSING NFSFKHEPSA EFEKNYAFTM HYPAATLAGA QSHGSIFSGT AAPRCEIPID NIMSFDSHSH HERVMSAQL
Target Information
NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis. It binds to the insulin gene E-box, and efficient DNA binding requires dimerization with another basic helix-loop-helix (bHLH) protein. Defects in NEUROD1 are associated with maturity onset diabetes of the young type VI (MODY6), a non-insulin-dependent diabetes mellitus characterized by autosomal dominant inheritance, onset in young adulthood, and impaired insulin secretion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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