Thermo Fisher Scientific CD8 beta Monoclonal Antibody (CT-CD8b)

Applications

Flow Cytometry (Flow)

• Tested Dilution: 0.1 µg/1×10⁶ cells
• Publications: View 2 publications

Miscellaneous PubMed (Misc)

• Publications: View 10 publications

Product Specifications

Additional Formats

• APC
• Biotin
• FITC
• PE
• Request custom conjugation

Product Specific Information

MA5-17843 targets CD8b/LYT3 in FACS applications and shows reactivity with Mouse samples.
The MA5-17843 immunogen is mouse CD8 β.

Target Information

The CD8B antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system.
The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules.
The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain.
Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
This gene encodes the CD8 beta chain isoforms.
Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described.
A pseudogene, also located on chromosome 2, has been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.