Thermo Fisher Scientific PKM Monoclonal Antibody (GT1810)
PKM 단백질을 인식하는 GT1810 클론의 마우스 단일클론 항체입니다. WB, IHC, ICC/IF 등 다양한 응용에 적합하며 높은 특이성과 재현성을 제공합니다. Protein G로 정제된 액상 형태로, -20°C에서 보관합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat, Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT1810 |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human PKM. The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.43 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898174 |
Product Specific Information
Centrifuge briefly prior to opening.
Target Information
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate.
This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones.
It also binds Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role in bacterial pathogenesis.
Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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