Thermo Fisher Scientific Fra1 Polyclonal Antibody
Fra1 단백질을 인식하는 Goat 폴리클로날 항체로 Western blot에 적합. Human에 반응하며 Bovine, Canine, Mouse 등에서도 예측 반응. 합성 펩타이드 면역원 사용. 액상 형태로 0.5 mg/mL 농도, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (QREIEELQKQKER) corresponding to the internal amino acids of FOSL1 (aa 148–161) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10981130 |
Product Specific Information
- Predicted to react with bovine, canine, mouse, porcine, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1,000.
Target Information
The v-Fos oncogene was initially detected in two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. Members of the c-Fos gene family, including c-Fos, Fos B, Fra-1, and Fra-2, encode nuclear phosphoproteins that are rapidly and transiently induced by various agents and function as transcriptional regulators for several genes. Unlike c-Jun proteins, which form homo- and heterodimers that bind to specific DNA response elements, c-Fos proteins are active only as heterodimers with members of the Jun gene family. Selected ATF/CREB family members can also form leucine zipper dimers with Fos and Jun, and different dimers exhibit differential specificity and affinity for AP-1 and CRE sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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