
Thermo Fisher Scientific BFSP1 Monoclonal Antibody (OTI1F1), TrueMAB
Human BFSP1 단백질(aa 405-665)을 인식하는 마우스 단클론 항체로 Western blot에 최적화됨. 무보존제, 동결건조 형태로 제공되며 재구성 후 1 mg/mL 농도 유지. 연구용으로만 사용 가능.
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Thermo Fisher Scientific BFSP1 Monoclonal Antibody (OTI1F1), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 405–665 of human BFSP1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, an additional desalting step is recommended (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
More than 99% of the vertebrate ocular lens consists of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (phakinin) and filensin (product of BFSP1 gene), are expressed after fiber cell differentiation begins. Both proteins form part of the beaded filament (BF), a unique cytoskeletal structure.
Mutations in BFSP1 cause autosomal recessive cortical juvenile-onset cataract. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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