Thermo Fisher Scientific Pan Ras Recombinant Rabbit Monoclonal Antibody (ARC1112)
Pan Ras 단백질을 인식하는 재조합 토끼 단일클론 항체로, Western blot, ICC/IF, ELISA 등 다양한 응용에 적합합니다. HEK293 발현 시스템에서 생산되었으며, 고순도 친화 크로마토그래피 정제 제품입니다. 인간, 생쥐, 랫드 시료에 반응하며 연구용으로만 사용됩니다.
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- MA535567
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- pk
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Thermo Fisher Scientific Pan Ras Recombinant Rabbit Monoclonal Antibody (ARC1112)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1112 |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human NRAS (P01111) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849467 |
Product Specific Information
Immunogen sequence:
MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG QEEYSAMRDQ YMRTGEGFLC VFAINNSKSF ADINLYREQI
Target Information
The Ras oncogene family encodes proteins involved in signal transduction pathways. These proteins bind GTP and GDP and possess intrinsic GTPase activity. They cycle between the plasma membrane and Golgi apparatus, regulated by palmitoylation. Mutations in these genes can lead to Costello syndrome and are associated with various cancers such as bladder, thyroid, and oral squamous cell carcinoma. Multiple transcript variants exist, encoding different isoforms.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: MA5-35567_Pan_Ras_P01111-1_Rabbit.svg, MA5-35567_Pan_Ras_P01112-1_Rabbit.svg, MA5-35567_Pan_Ras_P01116-1_Rabbit.svg)
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