Thermo Fisher Scientific Calpain 1 Polyclonal Antibody
Calpain 1 단백질을 검출하기 위한 Thermo Fisher Scientific의 염소 폴리클로날 항체. Western blot 및 IHC(파라핀)에서 검증됨. 고순도 액상 형태로 제공되며, 인간 반응성. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.3–1 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-SEKSAGTVELDD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933669 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Target Information
The calpains, including Calpain 1 (CAPN1), are calcium-activated neutral proteases that function as nonlysosomal, intracellular cysteine proteases. Mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large catalytic subunits and a common small regulatory subunit.
This gene encodes the large subunit of the ubiquitous enzyme Calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.
Diseases associated with CAPN1 include Spastic Paraplegia 76 (Autosomal Recessive) and Spasticity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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