
Thermo Fisher Scientific JAM-A (CD321) Monoclonal Antibody (BV12), FITC
JAM-A(CD321)을 인식하는 BV12 클론 단일클론 항체로, FITC로 표지되어 있습니다. Western blot, ICC/IF, Flow cytometry, IP, Inhibition assay에 사용 가능합니다. 마우스 시료에 반응하며, 단백질 G로 정제된 액상 형태입니다. 연구용으로만 사용하십시오.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:50 |
| Flow Cytometry (Flow) | 1:50 |
| Immunoprecipitation (IP) | 1:50 |
| Inhibition Assays (IA) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BV12 |
| Immunogen | H5V endothelial cells |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_3093284 |
Product Specific Information
The monoclonal antibody BV12 recognizes junctional adhesion molecule-A (JAM-A), also known as JAM-1 and the mouse platelet F11-Receptor (F11R). JAM-A is a cell adhesion molecule (CAM) involved in cell-cell contact and junctional integrity.
Target Information
CD321 (F11R, JAM-1, JAM-A) is a cell-surface adhesion molecule belonging to the immunoglobulin superfamily.
It is a 32–41 kDa glycoprotein containing two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail.
CD321 forms homodimers at the membrane and associates with other membrane proteins such as integrins.
CD321 is expressed on various cell types including:
- Leukocytes
- Platelets
- Erythrocytes
- Stem cells
- Epithelial and endothelial cells
It plays key roles in:
- Mediating cell-cell contact
- Maintaining epithelial and endothelial barriers
- Hematopoiesis and angiogenesis
- Tumor proliferation, invasion, and metastasis
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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