Thermo Fisher Scientific Calnexin Polyclonal Antibody
Calnexin 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, IP 등 다양한 응용에 사용 가능. 인간 Calnexin의 542–592번 잔기 영역을 면역원으로 제작. 액상 형태, 1 mg/mL 농도, 4°C 보관. Rat, Dog, Orangutan에서도 반응 예측됨.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Calnexin Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution / Amount |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 542 and 592 of human Calnexin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Rat, Dog, and Orangutan
Target Information
Calnexin (also known as IP90, p88, p90) is an approximately 90 kDa integral membrane protein of the endoplasmic reticulum (ER).
It functions as a molecular chaperone, aiding in the proper folding and assembly of polypeptides and multisubunit proteins.
Calnexin associates with MHC class I heavy chains, partial T cell receptor complexes, and B cell membrane immunoglobulins, but not with fully assembled receptors.
It retains incompletely or improperly folded proteins within the ER.
Unlike soluble ER proteins containing the KDEL sequence, calnexin lacks this motif but contains positively charged cytosolic residues ensuring ER retention.
The protein has a large ER luminal domain (461 amino acids), a transmembrane region (22 amino acids), and a cytoplasmic tail (89 amino acids).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.