Thermo Fisher Scientific SPACA1 Polyclonal Antibody
Human SPACA1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:200–1:500 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존. 정자막 단백질 연구 및 생식 관련 연구용에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SPACA1. Recombinant protein control fragment (Product # RP-102938) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2647766 |
Product Specific Information
Immunogen sequence:
LRQDQQSIIL VNDSAILEVR KESHPLAFEC DTLDNNEIVA TIKFTVYTSS ELQMRRSSLP A
Highest antigen sequence identity to orthologs:
- Mouse: 70%
- Rat: 69%
Target Information
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens.
The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa, where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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