Thermo Fisher Scientific TAF1B Monoclonal Antibody (OTI2A12), TrueMAB
TAF1B 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot에 최적화됨. Human 시료 반응성. Lyophilized 형태로 제공되며, PBS buffer와 trehalose 포함. RNA polymerase I 전사 개시 복합체 연구에 적합.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A12 |
| Immunogen | Human recombinant protein fragment (amino acids 1–208 of human TAF1B produced in E.coli) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
TAF1B is a component of the RNA polymerase I core factor complex acting as a GTF2B/TFIIB-like factor. It plays a key role in transcription initiation, including preinitiation complex (PIC) assembly and post-polymerase recruitment events in Pol I transcription.
TAF1B binds rDNA promoters and contributes to Pol I recruitment as part of the SL1/TIF-IB complex and potentially via direct interaction with RRN3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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