Thermo Fisher Scientific TrxR1 Polyclonal Antibody
TrxR1 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간, 마우스, 랫트 시료에 반응합니다. Western blot 및 IHC(P)에서 사용 가능하며, Affinity chromatography로 정제되었습니다. PBS/50% glycerol 완충액에 보관되며 -20°C에서 안정적으로 저장됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TXNRD1 (Accession Q16881), corresponding to amino acid residues Y302–D323. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900728 |
Product Specific Information
This antibody detects endogenous levels of total TXNRD1.
Target Information
This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates and plays a role in selenium metabolism and protection against oxidative stress.
The functional enzyme is thought to be a homodimer using FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination.
The 3′ UTR of selenocysteine-containing genes has a common stem-loop structure, the SECIS (Sec Insertion Sequence), necessary for recognizing UGA as a Sec codon rather than a stop signal.
Alternative splicing results in several transcript variants encoding the same or different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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