Thermo Fisher Scientific TNNI2 Polyclonal Antibody
TNNI2 단백질을 인식하는 Thermo Fisher Scientific의 산양 유래 폴리클로날 항체. 인간, 마우스, 랫트 반응성. Western blot 및 Peptide ELISA에 적합. 액상 형태, 0.5 mg/mL 농도, -20°C에서 보관.
- 카탈로그번호
- PA5143044
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific TNNI2 Polyclonal Antibody
Applications
- Western Blot (WB): 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-EVRVQKTSKELED |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933683 |
Product Specific Information
- This antibody is expected to recognize both reported isoforms (NP_003273.1; NP_001139313.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:8,000.
Target Information
The TNNI2 gene encodes a fast-twitch skeletal muscle protein, part of the troponin complex (troponin T, C, and I subunits). The complex regulates calcium-dependent muscle contraction.
Mouse studies indicate expression in vascular smooth muscle, suggesting a role in smooth muscle regulation.
Beyond muscle tissues, TNNI2 is found in corneal epithelium and cartilage (inhibitor of angiogenesis), and mammary gland (co-activator of estrogen receptor-related receptor alpha).
It also suppresses tumor growth in human ovarian carcinoma.
Mutations in TNNI2 cause myopathy and distal arthrogryposis type 2B.
Alternatively spliced transcript variants have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(PA5-143044_TNNI2_P48788-1_Goat.svg, PA5-143044_TNNI2_P48788-1_Goat_PDP.jpeg)
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