Thermo Fisher Scientific PU.1 (SPI-1) (B-Cell Marker) Monoclonal Antibody (PU1/2118)
PU.1(SPI-1) 단백질을 인식하는 Mouse monoclonal 항체로, B세포 및 골수세포 발현 연구에 적합. IHC(P) 및 IHC(PFA)에서 사용 가능하며, Protein A/G로 정제된 1 mg/mL 액상 형태. PBS(pH 7.4) 버퍼에 보존제 없이 보관.
- 카탈로그번호
- 6688-MSM1-P1ABX
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PU1/2118 |
| Immunogen | Recombinant human PU.1 fragment (aa 16–170) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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