Thermo Fisher Scientific PPP1R3B Polyclonal Antibody
Thermo Fisher Scientific의 PPP1R3B 폴리클로날 항체는 인간 단백질에 반응하며, Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제된 액상 항체로, 농도는 1.57 mg/mL입니다. 단기 4°C, 장기 -20°C 보관을 권장합니다.
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human PPP1R3B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.57 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792824 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (82%), Rat (87%), Bovine (85%).
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of PP1 with enzymes of glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase, thereby limiting glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Overexpression in hepatocytes dramatically increases basal and insulin-stimulated glycogen synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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