Thermo Fisher Scientific ZP4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide derived from the internal region of human ZP4

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2556113

Target Information

The mammalian zona pellucida is composed of four major glycoproteins, ZP1, ZP2, ZP3 and ZP4, which may act as sperm receptors. Two forms of porcine ZP4 peptides exist: one consisting of 128 amino acid residues and the other of 133 amino acid residues. These two peptides are identical, except the larger form contains an additional five amino acid sequence at its carboxy-terminal end. Both peptides have two potential N-linked glycosylation sites. The smaller peptide shares 39.1% identity with the amino-terminal region of mouse ZP2 polypeptide. Based on results from animal studies, ZP4 antigen is a promising candidate for the development of a contraceptive vaccine.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.