Thermo Fisher Scientific TIS11D Polyclonal Antibody
Rabbit 유래 Polyclonal TIS11D 항체로 Western blot에 적합. 인간 TIS11D 단백질의 내부 영역에서 유래한 합성 펩타이드로 면역화됨. 비결합(Unconjugated) 형태로 1 mg/mL 농도, 액상 형태로 제공. -20°C 보관, 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human TISD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555207 |
Target Information
TIS11D, also known as ZFP36LA (zinc finger protein 36, C3H type-like 2), BRF2 (butyrate response factor 2), ERF2, or RNF162C, is a 494 amino acid protein localized in the nucleus and containing two CSH1-type zinc fingers.
As a member of the TIS11 family of early response proteins, TIS11D functions as a nuclear transcription factor that binds to the 5′UUAUUUAUUU-3′ core RNA sequence, potentially regulating growth factor-induced cellular responses.
The gene encoding TIS11D is located on human chromosome 2, which contains over 1,400 genes and represents approximately 8% of the human genome.
Mutations in the ABCA12 gene are associated with Harlequin ichthyosis, while defects in ABCG5 and ABCG8 genes are linked to sitosterolemia, a lipid metabolic disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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