Thermo Fisher Scientific EXOSC7 Monoclonal Antibody (OTI2E5), TrueMAB

Applications and Tested Dilutions

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

EXOSC7 is a non-catalytic component of the RNA exosome complex, which exhibits 3’→5’ exoribonuclease activity and is involved in various RNA processing and degradation pathways.
In the nucleus, it contributes to the maturation of stable RNA species (rRNA, snRNA, snoRNA), elimination of RNA processing by-products, and degradation of defective mRNAs.
In the cytoplasm, it participates in mRNA turnover, degradation of unstable AU-rich element-containing mRNAs, and RNA surveillance pathways.
The RNA exosome complex may also play roles in Ig class switch recombination (CSR) and somatic hypermutation (SHM).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.