Thermo Fisher Scientific Human NOD3 Synthetic Peptide
인간 NOD3 단백질 중심부 18개 아미노산 서열에 해당하는 합성 펩타이드. 폴리클로날 항체 PA5-21016의 블로킹 펩타이드로 사용 가능. 면역 방어 관련 NOD 패밀리 연구용. 액상 형태, PBS 버퍼에 0.1% BSA 및 0.02% sodium azide 포함.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 18 amino acids near the center of human NOD3.
PEP-1130 can be used as a blocking peptide with polyclonal antibody PA5-21016.
Target Information
NOD3 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins involved in innate immune defense.
Also known as NLR family CARD containing 3 (NLRC3), NOD3 is predominantly expressed in the immune system, particularly in T lymphocytes.
Its expression is strongly down-regulated following stimulation of the T-cell receptor complex and CD28, suggesting that NOD3 plays a role in attenuating T cell activation.
NOD3 inhibits NF-κB, AP-1, and NFAT transcriptional activation in Jurkat T cells downstream of CD3/CD28 stimulation or treatment with PMA/ionomycin, and decreases IL-2 and CD25 mRNA induction in activated cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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