Thermo Fisher Scientific Ku80 Monoclonal Antibody (S.669.4)
Ku80 단백질을 표적으로 하는 Rabbit Monoclonal Antibody로, Western blot, IHC, ICC, IP, ChIP 등 다양한 응용에 사용 가능. 인간 및 비인간 영장류 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:400–1:1,600 |
| Immunocytochemistry (ICC/IF) | 1:200–1:800 |
| Immunoprecipitation (IP) | 1:50 |
| ChIP assay (ChIP) | 2.5 µg/10^6 cells |
| in situ PLA (PLA) | – |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S.669.4 |
| Immunogen | Synthetic peptide corresponding to the carboxy terminus of human Ku80 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 7 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10979323 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein, also known as ATP-dependent DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase and functions with the DNA ligase IV–XRCC4 complex in repair of DNA double-strand breaks by non-homologous end joining and in V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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