Thermo Fisher Scientific CP110 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human CP110 protein (residues 575–625). Validated for WB and IP. Supports centrosome duplication and ciliogenesis studies. Supplied as liquid, 0.2 mg/mL, store at 4°C. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 575 and 625 of human CP110 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole, thereby preventing cilia formation (PubMed:17719545, PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA), thereby affecting the fusion of recycling endosomes to basal bodies during cilia formation. Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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