Thermo Fisher Scientific GRASP1 Polyclonal Antibody
GRASP1 단백질을 인식하는 Goat 유래 Polyclonal 항체로, Human 시료에 반응합니다. Immunohistochemistry (Paraffin)에서 사용 가능하며, 0.5 mg/mL 농도의 액상 형태로 제공됩니다. Ammonium sulfate 침전으로 정제되었으며, -20°C에서 보관합니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested dilution 3.75 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence LREQTTGLAAELQ-C (aa 359–371) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2932772 |
Product Specific Information
- This antibody is expected to recognize both reported isoforms (NP_064522.3; NP_997555.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
- Preliminary analysis showed no signal in Western Blot.
Target Information
PDZ domain-containing proteins, such as PSD-95 and GRIP, are key regulators of glutamate receptor plasticity. GRIP-associated proteins (GRASPs) bind to distinct PDZ domains within GRIP and play critical roles in glutamate receptor regulation. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). It may regulate neuronal ras signaling and contribute to AMPA receptor distribution modulation by NMDA receptor activity (Ye et al., 2000).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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