Thermo Fisher Scientific CtBP2 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:200–1:500

Immunocytochemistry (ICC/IF)

• Tested Dilution: 0.25–2 µg/mL

Product Specifications

Product Specific Information

Immunogen sequence:
VPSYGVLGSR TSWDPMQGRS PALQDAGHLY RDPGGKMIPQ GRQTQSRAAS PGRYGREQPD TRYGAEVPAY PLSQVFSDIS ERPIDPAP

Highest antigen sequence identity to the following orthologs:

• Mouse: 63%
• Rat: 62%

Target Information

This gene produces alternative transcripts encoding two distinct proteins.

• One protein acts as a transcriptional repressor.
• The other isoform is a major component of specialized synapses known as synaptic ribbons.
  Both proteins contain a NAD⁺ binding domain similar to NAD⁺-dependent 2-hydroxyacid dehydrogenases.

A portion of the 3′ untranslated region was used to map this gene to chromosome 21q21.3; however, similar loci elsewhere in the genome are likely.
Blast analysis shows that this gene is present on chromosome 10.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.