Thermo Fisher Scientific CD11b Monoclonal Antibody (VIM12), TRI-COLOR
TRI-COLOR™ 형광 표지된 CD11b 단클론 항체(VIM12)는 인간 CD11b를 검출하기 위한 Flow Cytometry에 적합합니다. 488 nm 레이저로 다중 색상 분석 가능하며, 액상 형태로 4°C 암저장 조건을 권장합니다. Monocyte, macrophage, microglia 표지에 유용합니다.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications
- Flow Cytometry (Flow)
Tested Dilution: Assay-Dependent
Publications: - References
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | VIM12 |
| Immunogen | Human CD11b (Mac-1) |
| Conjugate | TRI-COLOR™ |
| Excitation / Emission Max | 567 / 671 nm |
| Form | Liquid |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Wet ice |
Additional Formats
Product Specific Information
The TRI-COLOR® conjugate is a tandem R-phycoerythrin (PE)-Cy5 conjugate that allows simultaneous multicolor labeling and detection of multiple targets using a single excitation source—the 488 nm line of the argon-ion laser.
Target Information
CD11b (integrin alpha-M, ITGAM, integrin alpha-X, ITGAX) is a 165 kDa adhesion molecule that associates non-covalently with integrin beta-2 (CD18). The CD11b/CD18 heterodimeric complex is known as integrin alpha-M beta-2, Mac-1, and CR3 (complement receptor 3).
CD11b is expressed on:
- Monocytes/macrophages
- Granulocytes
- Activated lymphocytes
- Subsets of NK cells and dendritic cells
- Microglia in the brain
Functions as receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X. These adhesions are critical for cell-cell and cell-matrix interactions.
Expression levels:
- 8% of spleen cells
- 44% of bone marrow cells
- <1% of thymocytes
Commonly used as a microglial marker in nervous tissue. Expression increases during monocyte maturation and varies among tissue macrophages. Peritoneal macrophages express higher levels of CD11b than splenic macrophages.
Diseases associated with CD11b dysfunction include systemic lupus erythematosus and ITGAM-related susceptibility to systemic lupus erythematosus.
Analyte Specific Reagent
제품 이미지
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific CD11b Monoclonal Antibody (VIM12), Alexa Fluor 700
739,000원
Thermo Fisher Scientific
Thermo Fisher Scientific CD11b Monoclonal Antibody (VIM12), APC
665,700원
Thermo Fisher Scientific
Thermo Fisher Scientific CD11b Monoclonal Antibody (VIM12), TRI-COLOR
438,200원
Thermo Fisher Scientific
Thermo Fisher Scientific CD11b Monoclonal Antibody (VIM12), PE
534,700원
Thermo Fisher Scientific
Thermo Fisher Scientific CD11b Monoclonal Antibody (VIM12)
319,700원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|